RITA1 Antikörper (C-Term)

Produktnummer ABIN5514467

Der Kaninchen Polyklonal anti-RITA1 Antikörper (ABIN5514467) detektiert spezifisch RITA1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RITA1 Antikörper (C-Term) (ABIN5514467)

Target: RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RITA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RITA1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: RITA1 Antibody - C-terminal

Sequenz: TNGPQDLRPS TSGVTFRSPL VTSRARSVSI SVPSTPRRGG ATQKPKPPWK

Produktmerkmale: This is a rabbit polyclonal antibody against RITA1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RITA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75829-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RITA1

Target: RITA1 (Tyrosine-Based Site-Specific Recombinase (Recombinase Triad in CMGI-2) (RITA1))

Andere Bezeichnung: RITA1

Hintergrund:

Background Information: RITA1 is a tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. It shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. And it may play a role in neurogenesis.

Alternative Symbols: RITA, C12orf52

Molekulargewicht: 29 kDa

Gen-ID: 84934

NCBI Accession: XP_005254029

UniProt: Q96K30