PDE10A Antikörper (N-Term)
Kurzübersicht für PDE10A Antikörper (N-Term) (ABIN5514456)
Target
Alle PDE10A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- PDE10A Antibody - N-terminal region
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Sequenz
- SLHPQVLDEF VSESVSAETV EKWLKRKNNK SEDESAPKEV SRYQDTNMQG
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Homologie
- Dog: 93%, Horse: 93%, Human: 100%, Rabbit: 86%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PDE10A. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDE10A
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72732-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDE10A (phosphodiesterase 10A (PDE10A))
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Andere Bezeichnung
- PDE10A
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Hintergrund
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Background Information: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.
Alternative Symbols: ADSD2, IOLOD, HSPDE10A, PDE10A19, LINC00473
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Molekulargewicht
- 85kDa
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Gen-ID
- 10846
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UniProt
- Q9Y233
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Pathways
- cAMP Metabolic Process
Target
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