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TTHY Antikörper (N-Term)

TTHY Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5514452
  • Target Alle TTHY Produkte
    TTHY (Thymocyte Alloantigen (TTHY))
    Bindungsspezifität
    N-Term
    Reaktivität
    Human
    Wirt
    Kaninchen
    Klonalität
    Polyklonal
    Applikation
    Western Blotting (WB)
    Sequenz
    CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT
    Produktmerkmale
    This is a rabbit polyclonal antibody against TTHY. It was validated on Western Blot.
    Aufreinigung
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTHY
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TTHY (Thymocyte Alloantigen (TTHY))
    Andere Bezeichnung
    TTHY (TTHY Produkte)
    Synonyme
    thymocyte alloantigen antikoerper, Tthy antikoerper
    Hintergrund
    This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

    Alias Symbols: TTR, PALB,

    Protein Size: 147
    Gen-ID
    7276
    NCBI Accession
    NP_000362
    UniProt
    P02766
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