Glucosylceramidase Antikörper (N-Term)

Produktnummer ABIN5514399

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Glucosylceramidase in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen und Ratte.

Kurzübersicht für Glucosylceramidase Antikörper (N-Term) (ABIN5514399)

Target: Glucosylceramidase (GLCM)

Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glucosylceramidase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glucosylceramidase Antikörper

Bindungsspezifität: N-Term

Sequenz: FSSPSREECP KPLSRVSIMA GSLTGLLLLQ AVSWASGARP CIPKSFGYSS

Homologie: Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 75%, Pig: 79%, Rabbit: 75%, Rat: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against GLCM. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLCM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Glucosylceramidase

Target: Glucosylceramidase (GLCM)

Andere Bezeichnung: GLCM

Hintergrund: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Alias Symbols: GBA, GC, GLUC,

Protein Interaction Partner: NUDCD1, UBC, ITCH, ATP6V1B1, SNCA, FBXO6, TCP1, CBL, NEDD4, PARK2, HSP90AA1, HSPA4, PSAP,

Protein Size: 536

Gen-ID: 2629

NCBI Accession: XP_006711333

UniProt: P04062