GBA Antikörper (N-Term)

Produktnummer ABIN5514399

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GBA in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für GBA Antikörper (N-Term) (ABIN5514399)

Target: GBA (Glucosidase, Beta, Acid (GBA))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GBA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GBA Antibody - N-terminal region

Sequenz: FSSPSREECP KPLSRVSIMA GSLTGLLLLQ AVSWASGARP CIPKSFGYSS

Homologie: Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 75%, Pig: 79%, Rabbit: 75%, Rat: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against GLCM. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLCM

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61323-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Andere Bezeichnung: GBA

Hintergrund:

Background Information: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Gene Name: glucosylceramidase beta

Alternative Symbols: GCB, GBA1, GLUC

Protein Name: glucosylceramidase

Molekulargewicht: 58kDa

Gen-ID: 2629

NCBI Accession: XP_006711333

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process