HLA-DOA Antikörper (N-Term)

Produktnummer ABIN5514394

Produktdetails anti-HLA-DOA Antikörper

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Pferd, Schwein, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLA-DOA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LMTLLSPQEA GATKADHMGS YGPAFYQSYG ASGQFTHEFD EEQLFSVDLK

Homologie: Cow: 83%, Horse: 85%, Human: 100%, Pig: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against DOA. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DOA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HLA-DOA

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Andere Bezeichnung: DOA (HLA-DOA Produkte)

Synonyme: HLA-DNA antikoerper, HLA-DZA antikoerper, HLADZ antikoerper, major histocompatibility complex, class II, DO alpha antikoerper, HLA-DOA antikoerper

Hintergrund: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Alias Symbols: HLA-DOA, HLA-DNA, HLA-DZA,

Protein Interaction Partner: REL, UBC, HLA-DMA,

Protein Size: 250

Gen-ID: 3111

NCBI Accession: NP_002110

UniProt: P06340