CHORDC1 Antikörper (N-Term)

Produktnummer ABIN5514389

Produktdetails anti-CHORDC1 Antikörper

Target: CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHORDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TYHPGVPVFH DALKGWSCCK RRTTDFSDFL SIVGCTKGRH NSEKPPEPVK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CHRD1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CHRD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CHORDC1

Target: CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))

Andere Bezeichnung: CHRD1 (CHORDC1 Produkte)

Hintergrund: CHRD1 regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. It is proposed to act as co-chaperone for HSP90. CHRD1 may play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, it has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. It is involved in stress response. It prevents tumorigenesis.

Alias Symbols: CHORDC1, CHP1,

Protein Interaction Partner: TARS2, XPO5, CDC37L1, CDC37, TOMM34, AHSA1, TUBA1B, TTC4, PPP5C, HSP90AB1, HSP90AA1, FKBP5, FKBP4, BCCIP, NAGK, C11orf58, SUGT1, KYNU, TCEA1, SORD, SMS, PGD, CSE1L, XPO1, UBC, PAK1, CHORDC1,

Protein Size: 332

Gen-ID: 26973

NCBI Accession: NP_036256

UniProt: Q9UHD1