Cereblon (CRBN) (AA 1-442) Antikörper

Details zu Produkt Nr. ABIN526543
Antigen
Epitop
AA 1-442
4
2
2
2
1
1
1
Reaktivität
Human
40
32
28
3
3
3
3
2
1
1
1
1
1
Wirt
Maus
39
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
30
14
13
10
10
5
4
4
1
1
Optionen
Verwendungszweck Mouse polyclonal antibody raised against a full-length human CRBN protein.
Marke MaxPab®
Immunogen

immunogen: CRBN (NP_057386.2, 1 a.a. ~ 442 a.a) full-length human protein.

Immunogen Sequence: MAGEGDQQDAAHNMGNHLPLLPAESEEEDEMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEFHGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL
Kreuzreaktivität Human
Antigen
Andere Bezeichnung CRBN (CRBN Antibody Abstract)
Hintergrund Full Gene Name: cereblon
Synonyms: DKFZp781K0715,MGC27358,MRT2A
Gen-ID 51185
NCBI Accession NP_057386, NM_016302
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Kommentare

Product Quality tested by: Antibody reactive against mammalian transfected lysate.
Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer In 1x PBS, pH 7.4
Handhabung Aliquot to avoid repeated freezing and thawing.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Image no. 1 for anti-Cereblon (CRBN) (AA 1-442) antibody (ABIN526543) Western Blot analysis of CRBN expression in transfected 293T cell line by CRBN MaxPab...
Produkt verwendet in: Peng, Li, Clarkson, Pehar, Lao, Hillmer, Barnhart, Christian, Mitchell, Bendlin, Sandor, Puglielli: "Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 20, pp. 6772-89, 2014 (PubMed).

Liu, Ye, Zou, Xu, Feng, Zou, Chen, Li, Cang: "CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis." in: Nature communications, Vol. 5, pp. 3924, 2014 (PubMed).

Charoenfuprasert, Yang, Lee, Chao, Chu, Lai, Hsu, Chang, Chen, Chen, Chang, Leu, Shih: "Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer." in: Oncogene, Vol. 30, Issue 33, pp. 3570-84, 2011 (PubMed).