Cereblon (CRBN) (AA 1-442) Antikörper

Details zu Produkt Nr. ABIN526543
Antigen
  • zgc:92404
  • mrt2a
  • F3N11.21
  • MRT2
  • MRT2A
  • 2610203G15Rik
  • 2900045O07Rik
  • AF229032
  • AW108261
  • piL
  • cereblon
  • ATP-dependent protease La (LON) domain protein
  • crbn
  • CRBN
  • AT2G25740
  • Crbn
Epitop
AA 1-442
4
2
2
2
1
1
1
Reaktivität
Human
43
33
30
3
3
3
3
2
1
1
1
1
1
Wirt
Maus
41
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
32
14
13
11
6
5
4
3
1
1
Optionen
Marke MaxPab®
Immunogen CRBN (NP_057386.2, 1 a.a. ~ 442 a.a) full-length human protein.
Immunogen sequence: MAGEGDQQDA AHNMGNHLPL LPAESEEEDE MEVEDQDSKE AKKPNIINFD TSLPTSHTYL GADMEEFHGR TLHDDDSCQV IPVLPQVMMI LIPGQTLPLQ LFHPQEVSMV RNLIQKDRTF AVLAYSNVQE REAQFGTTAE IYAYREEQDF GIEIVKVKAI GRQRFKVLEL RTQSDGIQQA KVQILPECVL PSTMSAVQLE SLNKCQIFPS KPVSREDQCS YKWWQKYQKR KFHCANLTSW PRWLYSLYDA ETLMDRIKKQ LREWDENLKD DSLPSNPIDF SYRVAACLPI DDVLRIQLLK IGSAIQRLRC ELDIMNKCTS LCCKQCQETE ITTKNEIFSL SLCGPMAAYV NPHGYVHETL TVYKACNLNL IGRPSTEHSW FPGYAWTVAQ CKICASHIGW KFTATKKDMS PQKFWGLTRS ALLPTIPDTE DEISPDKVIL CL
Kreuzreaktivität Human
Antigen
Andere Bezeichnung CRBN (CRBN Antibody Abstract)
Hintergrund Full Gene Name: cereblon
Synonyms: DKFZp781K0715,MGC27358,MRT2A
Gen-ID 51185
NCBI Accession NP_057386, NM_016302
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Kommentare

Product Quality tested by: Antibody reactive against mammalian transfected lysate.

Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer In 1x PBS, pH 7.4
Handhabung Aliquot to avoid repeated freezing and thawing.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Western Blotting (WB) image for anti-Cereblon (CRBN) (AA 1-442) antibody (ABIN526543) Western Blot analysis of CRBN expression in transfected 293T cell line by CRBN MaxPab...
Produkt verwendet in: Peng, Li, Clarkson, Pehar, Lao, Hillmer, Barnhart, Christian, Mitchell, Bendlin, Sandor, Puglielli: "Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 20, pp. 6772-89, 2014 (PubMed).

Liu, Ye, Zou, Xu, Feng, Zou, Chen, Li, Cang: "CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis." in: Nature communications, Vol. 5, pp. 3924, 2014 (PubMed).

Charoenfuprasert, Yang, Lee, Chao, Chu, Lai, Hsu, Chang, Chen, Chen, Chang, Leu, Shih: "Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer." in: Oncogene, Vol. 30, Issue 33, pp. 3570-84, 2011 (PubMed).

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