CRBN Antikörper (AA 1-442)
Kurzübersicht für CRBN Antikörper (AA 1-442) (ABIN526543)
Target
Alle CRBN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-442
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Verwendungszweck
- Mouse polyclonal antibody raised against a full-length human CRBN protein.
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Sequenz
- MAGEGDQQDA AHNMGNHLPL LPAESEEEDE MEVEDQDSKE AKKPNIINFD TSLPTSHTYL GADMEEFHGR TLHDDDSCQV IPVLPQVMMI LIPGQTLPLQ LFHPQEVSMV RNLIQKDRTF AVLAYSNVQE REAQFGTTAE IYAYREEQDF GIEIVKVKAI GRQRFKVLEL RTQSDGIQQA KVQILPECVL PSTMSAVQLE SLNKCQIFPS KPVSREDQCS YKWWQKYQKR KFHCANLTSW PRWLYSLYDA ETLMDRIKKQ LREWDENLKD DSLPSNPIDF SYRVAACLPI DDVLRIQLLK IGSAIQRLRC ELDIMNKCTS LCCKQCQETE ITTKNEIFSL SLCGPMAAYV NPHGYVHETL TVYKACNLNL IGRPSTEHSW FPGYAWTVAQ CKICASHIGW KFTATKKDMS PQKFWGLTRS ALLPTIPDTE DEISPDKVIL CL
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Kreuzreaktivität
- Human
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Produktmerkmale
- Antibody reactive against mammalian transfected lysate.
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Immunogen
- CRBN (NP_057386.2, 1 a.a. ~ 442 a.a) full-length human protein.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1x PBS, pH 7.4
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Handhabung
- Aliquot to avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 20, pp. 6772-89, (2014) (PubMed).
: "CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis." in: Nature communications, Vol. 5, pp. 3924, (2014) (PubMed).
: "Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer." in: Oncogene, Vol. 30, Issue 33, pp. 3570-84, (2011) (PubMed).
: "
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Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 20, pp. 6772-89, (2014) (PubMed).
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- CRBN (Cereblon (CRBN))
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Andere Bezeichnung
- CRBN
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Hintergrund
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Full Gene Name: cereblon
Synonyms: DKFZp781K0715,MGC27358,MRT2A -
Gen-ID
- 51185
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NCBI Accession
- NM_016302
Target
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