Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
No additive
Konservierungsmittel
Without preservative
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Jo, Hartman, DeBose-Boyd: "Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes." in: Molecular biology of the cell, Vol. 24, Issue 3, pp. 169-83, (2013) (PubMed).
Jo, Lee, Sguigna, DeBose-Boyd: "Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 51, pp. 20503-8, (2011) (PubMed).
Lee, Zhang, Feramisco, Gong, Ye: "Unsaturated fatty acids inhibit proteasomal degradation of Insig-1 at a postubiquitination step." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33772-83, (2008) (PubMed).
Target
FAF2
(Fas Associated Factor Family Member 2 (FAF2))