NT5C2 Antikörper (AA 1-561)

Produktnummer ABIN524900

Der Maus Monoklonal Anti-NT5C2-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, NT5C2 in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für NT5C2 Antikörper (AA 1-561) (ABIN524900)

Target: NT5C2 (5'-Nucleotidase, Cytosolic II (NT5C2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NT5C2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Klon: 3C1

Produktdetails anti-NT5C2 Antikörper

Bindungsspezifität: AA 1-561

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant NT5C2.

Sequenz: MSTSWSDRLQ NAADMPANMD KHALKKYRRE AYHRVFVNRS LAMEKIKCFG FDMDYTLAVY KSPEYESLGF ELTVERLVSI GYPQELLSFA YDSTFPTRGL VFDTLYGNLL KVDAYGNLLV CAHGFNFIRG PETREQYPNK FIQRDDTERF YILNTLFNLP ETYLLACLVD FFTNCPRYTS CETGFKDGDL FMSYRSMFQD VRDAVDWVHY KGSLKEKTVE NLEKYVVKDG KLPLLLSRMK EVGKVFLATN SDYKYTDKIM TYLFDFPHGP KPGSSHRPWQ SYFDLILVDA RKPLFFGEGT VLRQVDTKTG KLKIGTYTGP LQHGIVYSGG SSDTICDLLG AKGKDILYIG DHIFGDILKS KKRQGWRTFL VIPELAQELH VWTDKSSLFE ELQSLDIFLA ELYKHLDSSS NERPDISSIQ RRIKKVTHDM DMCYGMMGSL FRSGSRQTLF ASQVMRYADL YAASFINLLY YPFSYLFRAA HVLMPHESTV EHTHVDINEM ESPLATRNRT SVDFKDTDYK RHQLTRSISE IKPPNLFPLA PQEITHCHDE DDDEEEEEEE E

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: NT5C2 (AAH01595, 1 a.a. ~ 561 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-NT5C2 Antikörper (ABIN524900)

Cividini, Tozzi, Galli, Pesi, Camici, Dumontet, Jordheim, Allegrini: "Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf." in: PLoS ONE, Vol. 10, Issue 3, pp. e0121525, (2015) (PubMed).

Jordheim, Puy, Cros-Perrial, Peyrottes, Lefebvre, Périgaud, Dumontet: "Determination of the enzymatic activity of cytosolic 5'-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models." in: Analytical and bioanalytical chemistry, Vol. 407, Issue 19, pp. 5747-58, (2015) (PubMed).

Cividini, Cros-Perrial, Pesi, Machon, Allegrini, Camici, Dumontet, Jordheim, Tozzi: "Cell proliferation and drug sensitivity of human glioblastoma cells are altered by the stable modulation of cytosolic 5'-nucleotidase II." in: The international journal of biochemistry & cell biology, Vol. 65, pp. 222-9, (2015) (PubMed).

Kulkarni, Karlsson, Szekeres, Chibalin, Krook, Zierath: "Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle." in: The Journal of biological chemistry, Vol. 286, Issue 40, pp. 34567-74, (2011) (PubMed).

Details zu NT5C2

Target: NT5C2 (5'-Nucleotidase, Cytosolic II (NT5C2))

Andere Bezeichnung: NT5C2

Hintergrund: Full Gene Name: 5'-nucleotidase, cytosolic II
Synonyms: GMP,NT5B,PNT5,cN-II

Gen-ID: 22978