Aryl Hydrocarbon Receptor Antikörper (AA 721-820)

Produktnummer ABIN513203

Der Maus Monoklonal Anti-Aryl Hydrocarbon Receptor-Antikörper wurde für WB, ELISA, IF, IP und RNAi validiert. Er ist geeignet, Aryl Hydrocarbon Receptor in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für Aryl Hydrocarbon Receptor Antikörper (AA 721-820) (ABIN513203)

Target: Aryl Hydrocarbon Receptor (AHR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Aryl Hydrocarbon Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), RNA Interference (RNAi)

Klon: 3B12

Produktdetails anti-Aryl Hydrocarbon Receptor Antikörper

Bindungsspezifität: AA 721-820

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant AHR.

Sequenz: MGSFEPSPYP TTSSLEDFVT CLQLPENQKH GLNPQSAIIT PQTCYAGAVS MYQCQPEPQH THVGQMQYNP VLPGQQAFLN KFQNGVLNET YPAELNNINN

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: AHR (NP_001612, 721 a.a. ~ 820 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-Aryl Hydrocarbon Receptor Antikörper (ABIN513203)

Vogel, Khan, Leung, Gershwin, Chang, Wu, Haarmann-Stemmann, Hoffmann, Denison: "Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-?B." in: The Journal of biological chemistry, Vol. 289, Issue 3, pp. 1866-75, (2014) (PubMed).

Kalthoff, Winkler, Freiberg, Manns, Strassburg et al.: "Gender matters: estrogen receptor alpha (ER?) and histone deacetylase (HDAC) 1 and 2 control the gender-specific transcriptional regulation of human uridine diphosphate glucuronosyltransferases genes ..." in: Journal of hepatology, Vol. 59, Issue 4, pp. 797-804, (2013) (PubMed).

Vlachos, Schulte, Magiatis, Adema, Gaitanis: "Malassezia-derived indoles activate the aryl hydrocarbon receptor and inhibit Toll-like receptor-induced maturation in monocyte-derived dendritic cells." in: The British journal of dermatology, Vol. 167, Issue 3, pp. 496-505, (2012) (PubMed).

Schults, Timmermans, Godschalk, Theys, Wouters, van Schooten, Chiu: "Diminished carcinogen detoxification is a novel mechanism for hypoxia-inducible factor 1-mediated genetic instability." in: The Journal of biological chemistry, Vol. 285, Issue 19, pp. 14558-64, (2010) (PubMed).

Details zu Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Andere Bezeichnung: AHR

Hintergrund: Full Gene Name: aryl hydrocarbon receptor
Synonyms: bHLHe76

Gen-ID: 196

NCBI Accession: NM_001621

Pathways: Regulation of Cell Size