ICAM1 Antikörper

Produktnummer ABIN5067857

Der Maus Monoklonal anti-ICAM1 Antikörper (Klon LB-2) (ABIN5067857) detektiert spezifisch ICAM1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ICAM1 Antikörper (ABIN5067857)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: LB-2

Produktdetails anti-ICAM1 Antikörper

Verwendungszweck: CD54 Unconjugated Antibody

Produktmerkmale: The clone LB-2 specifically binds with CD54 also known as Intercellular adhesion molecule-1 (ICAM-1), a cell surface antigen expressed by various types of human immune and non-immune cells. CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the Ig supergene family and is a surrogate marker of antigen presenting cell activation. CD54 is expressed mostly on endothelial cells. It also weakly expressed by naive B and T cells and moderately expressed on activated B and T cells as well as monocytes. CD54 is highly expressed on human myeloma cells, Burkitt's lymphoma cells, erythroleukemia cells, and B-lymphoblastoid cells. The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: MHC Class II antigen negative human Blymphoblastoid cell line

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Andere Bezeichnung: CD54

NCBI Accession: NP_000192

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling