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Malondialdehyde Antikörper (PerCP)

Der Maus Monoklonal Anti-Malondialdehyde-Antikörper wurde für ELISA, WB, ICC, FACS und IF validiert. Er ist geeignet, Malondialdehyde in Proben von zu detektieren.
Produktnummer ABIN5067358

Kurzübersicht für Malondialdehyde Antikörper (PerCP) (ABIN5067358)

Target

Alle Malondialdehyde (MDA) Antikörper anzeigen
Malondialdehyde (MDA)

Reaktivität

Bitte anfragen

Wirt

  • 25
  • 2
  • 1
Maus

Klonalität

  • 25
  • 3
Monoklonal

Konjugat

  • 10
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser Malondialdehyde Antikörper ist konjugiert mit PerCP

Applikation

  • 24
  • 24
  • 22
  • 19
  • 13
  • 9
  • 6
  • 6
  • 5
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon

6H6
  • Spezifität

    Specific for MDA conjugated proteins. Does not detect free MDA. Does not cross-react with Acrolein, Crotonaldehyde, Hexanoyl Lysine, 4-HHE, 4-HNE, or Methylglyoxal modified proteins.

    Aufreinigung

    Protein G Purified

    Immunogen

    Synthetic Malondialdehyde modified Keyhole Limpet Hemocyanin (KLH).

    Isotyp

    IgG1
  • Applikationshinweise

    • WB (1:1000)
    • ICC/IF (1:50)
    • FACS (1:50)
    • FCM (1:50)
    • ELISA (1:1000)
    • optimal dilutions for assays should be determined by the user.

    Kommentare

    A 1:1000 dilution of ABIN5067358 was sufficient for detection of Malondialdehyde in 2 μg of Malondialdehyde conjugated to BSA by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary Antibody.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Conjugated antibodies should be stored at 4°C
  • Target

    Malondialdehyde (MDA)

    Andere Bezeichnung

    Malondialdehyde

    Substanzklasse

    Chemical

    Hintergrund

    Malondialdehyde (MDA) is the biomarker in greatest diagnostic use, due to its molecular stability. This three-carbon, low-molecular weight aldehyde has a strong affinity for amino acids, which results in adduct formation to both free amino acids and proteins. Increased MDA levels have been found at correlating levels in breast cancer, and lung cancer patients. Other diseased states with elevated MDA levels include diabetes and Alzheimer's disease. Multiple laboratory techniques exist for quantification of MDA levels, including the thiobarbituric acid reactive substances (TBARS) assay. In addition to use as a biomarker, MDA has been shown to have mutagenic effects on tissues themselves as adduct formation can result in DNA cross-linking.
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