WDR45 Antikörper (AA 312-322) (Atto 488)
Kurzübersicht für WDR45 Antikörper (AA 312-322) (Atto 488) (ABIN5066247)
Target
Alle WDR45 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 312-322
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Spezifität
- Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors.,Detects ~40 kDa.
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Peptide Affinity Purified
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Immunogen
- Synthetic peptide from the C-terminal of Human WIPI4 (aa. 312-322)
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Isotyp
- IgG
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Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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Kommentare
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A 1:1000 dilution of ABIN5066247 was sufficient for detection of WIPI4 in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- WDR45 (WD Repeat Domain 45 (WDR45))
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Andere Bezeichnung
- WDR45
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Hintergrund
- WIPI-4 is a 360 amino acid protein containing three WD repeats. Existing as three alternatively spliced isoforms, WIPI-4 is ubiquitously expressed but found at highest levels in heart and skeletal muscle. WD repeat proteins are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Diseases associated with this gene include neurodegeneration with brain iron accululation 5 and 4.
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Gen-ID
- 11152
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NCBI Accession
- NP_001025067
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UniProt
- Q9Y484
Target
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