Fibrillarin/Nop1p Nucleolar Marker Antikörper

Produktnummer ABIN504711

Der Maus Monoklonal anti-Fibrillarin/Nop1p Nucleolar Marker Antikörper (ABIN504711) detektiert spezifisch Fibrillarin/Nop1p Nucleolar Marker in IF und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Fibrillarin/Nop1p Nucleolar Marker Antikörper (ABIN504711)

Target: Fibrillarin/Nop1p Nucleolar Marker

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Applikation: Immunofluorescence (IF), Western Blotting (WB)

Produktdetails

Kreuzreaktivität: Caenorhabditis elegans (C. elegans), Fruchtfliege (Drosophila melanogaster), Human, Maus

Aufreinigung: Purified

Immunogen: Mice were injected with yeast nuclear preparations and hybridomas were screened by immunofluorescence on yeast cells and by western blotting on yeast protein homogenates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Antigendetails

Target: Fibrillarin/Nop1p Nucleolar Marker

Hintergrund: The Nop1p protein is 327 amino acids in size (34. 5 kDa), is essential for yeast viability, and is localized in the nucleoli (1). The systematic name for S. cerevisiae Nop1 is YDL014W, and it is now known to be part of the small subunit processome complex, involved in the processing of pre-18S ribosomal RNA. Nop1p is the yeast homologue of a protein apparently found in all eukaryotes and archea generally called fibrillarin. Fibrillarin/Nop1p is extraordinarily conserved, so that the yeast and human proteins are 67% identical, and the human protein can functionally replace the yeast protein.