CCR6 Antikörper

Produktnummer ABIN5027745

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CCR6 in WB. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CCR6 Antikörper (ABIN5027745)

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CCR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: ABM40H1

Produktdetails anti-CCR6 Antikörper

Aufreinigung: Protein G Chromatography

Immunogen: Full length recombinant protein from mCD196 was used as the immunogen for this antibody.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Andere Bezeichnung: mCD196

Hintergrund: CD196 displays a high degree of genetic homology between mouse and human. Moreover, in both species it is chromosomally segregated from the main chemokine receptor gene cluster. mCD196 is expressed by myeloid DCs (dendritic cells), mature B cells, subpopulations of memory/effector CD4+ and CD8+ T cells, but not plasmacytoid DCs or naï,ve T cells. mCD196 mediates their migration and function via stimulation with its ligand CCL20 (also known as macrophage inflammatory protein (MIP)-3alpha. mCD196 expression has been correlated with stage and prognosis in a variety of cancers including hepatocellular carcinoma, colorectal carcinoma, glioma, and non-small cell lung cancer. It is also believed to play a role in regulation of cancer progression.

Molekulargewicht: 47 kDa

Gen-ID: 1235

UniProt: P51684

Pathways: cAMP Metabolic Process