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CCR6 Antikörper

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CCR6 in WB. Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN5027745

Kurzübersicht für CCR6 Antikörper (ABIN5027745)

Target

Alle CCR6 Antikörper anzeigen
CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reaktivität

  • 73
  • 21
  • 13
  • 3
  • 1
Maus

Wirt

  • 47
  • 23
  • 6
  • 3
  • 1
  • 1
Ratte

Klonalität

  • 46
  • 32
  • 2
Monoklonal

Konjugat

  • 41
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCR6 Antikörper ist unkonjugiert

Applikation

  • 30
  • 24
  • 23
  • 16
  • 15
  • 7
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

ABM40H1
  • Aufreinigung

    Protein G Chromatography

    Immunogen

    Full length recombinant protein from mCD196 was used as the immunogen for this antibody.

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    WB: 2-4 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    PBS containing 0.05 % BSA, PH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target

    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

    Andere Bezeichnung

    mCD196

    Hintergrund

    CD196 displays a high degree of genetic homology between mouse and human. Moreover, in both species it is chromosomally segregated from the main chemokine receptor gene cluster. mCD196 is expressed by myeloid DCs (dendritic cells), mature B cells, subpopulations of memory/effector CD4+ and CD8+ T cells, but not plasmacytoid DCs or naï,ve T cells. mCD196 mediates their migration and function via stimulation with its ligand CCL20 (also known as macrophage inflammatory protein (MIP)-3alpha. mCD196 expression has been correlated with stage and prognosis in a variety of cancers including hepatocellular carcinoma, colorectal carcinoma, glioma, and non-small cell lung cancer. It is also believed to play a role in regulation of cancer progression.

    Molekulargewicht

    47 kDa

    Gen-ID

    1235

    UniProt

    P51684

    Pathways

    cAMP Metabolic Process
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