CRLF2 Antikörper (AA 97-252)
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- Target Alle CRLF2 Antikörper anzeigen
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
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Bindungsspezifität
- AA 97-252
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CRLF2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Protein G Chromatography
- Immunogen
- A partial length recombinant TSLPR protein (amino acids 97-252) was used as the immunogen for this antibody.
- Klon
- ABM28B6
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CRLF2 Primärantikörper
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anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) antibody
CRLF2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 81-180) antibodyCRLF2 Reaktivität: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-132) antibodyCRLF2 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4A11 unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) antibodyCRLF2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 71-120) antibodyCRLF2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibody (Carboxyfluorescein (CFS))CRLF2 Reaktivität: Maus FACS Wirt: Ziege Polyclonal Carboxyfluorescein (CFS)
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (Center) antibodyCRLF2 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibodyCRLF2 Reaktivität: Human WB, IHC (p), EIA Wirt: Maus Monoclonal 8H8 unconjugated
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- Applikationshinweise
- WB: 2-4 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Andere Bezeichnung
- TSLP Receptor (CRLF2 Produkte)
- Synonyme
- CRLF2 antikoerper, CRL2 antikoerper, CRLF2Y antikoerper, TSLPR antikoerper, CRLM2 antikoerper, Ly114 antikoerper, Tpte2 antikoerper, Tslpr antikoerper, Crl2 antikoerper, cytokine receptor like factor 2 antikoerper, cytokine receptor-like factor 2 antikoerper, CRLF2 antikoerper, Crlf2 antikoerper
- Hintergrund
- TSLPR (thymic stromal lymphopoietin receptor) also known as CRLF2 (cytokine receptor-like factor 2) is a member of type I cytokine receptor. It binds its ligand TSLP (thymic stromal lymphopoietin) as a heterodimer with IL7R. TSLP ligand is produced by epithelial cells in order to activate dendritic cells, and is involved in inflammation, allergic responses as well as B-cell precursor proliferation and survival. The interaction between TSLP and its heterodimeric receptor activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. High expression of CRLF2 is associated with a poor prognosis in adult and high-risk pediatric cases of B-ALL (B-cell acute lymphoblastic leukemias).
- Molekulargewicht
- 42 kDa
- Gen-ID
- 64109
- UniProt
- Q9HC73
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