IFRD1 Antikörper (AA 1-300)

Produktnummer ABIN5027565

Produktdetails anti-IFRD1 Antikörper

Target: IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant Tis7 protein (amino acids 1-300) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu IFRD1

Target: IFRD1 (Interferon Related Developmental Regulator 1 (IFRD1))

Andere Bezeichnung: Tis7 (IFRD1 Produkte)

Synonyme: im:7067566 antikoerper, si:dkey-192l17.2 antikoerper, wu:fi35f04 antikoerper, wu:fj67a06 antikoerper, zgc:154080 antikoerper, IFR1 antikoerper, PC4 antikoerper, TIS7 antikoerper, Ifnl antikoerper, Tis7 antikoerper, Pc4 antikoerper, interferon-related developmental regulator 1 antikoerper, interferon related developmental regulator 1 L homeolog antikoerper, interferon related developmental regulator 1 antikoerper, ifrd1 antikoerper, ifrd1.L antikoerper, IFRD1 antikoerper, Ifrd1 antikoerper

Hintergrund: Tis7/IFRD1 (interferon-related developmental regulator 1) is expressed by neutrophils as a key modifier gene in cystic fibrosis (CF) lung disease. It functions as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. In skeletal muscle cells, Tis7 is known to function as a coactivator of MyoD by promoting the transcriptional activity of myocyte enhancer factor 2C (MEF2C). Mutations in Tis7 are associated with sensory/motor neuropathy with ataxia.

Molekulargewicht: 55 kDa

Gen-ID: 3475

UniProt: O00458