POU3F2 Antikörper (AA 220-421)

Produktnummer ABIN5027442

Produktdetails anti-POU3F2 Antikörper

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Bindungsspezifität: AA 220-421

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU3F2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant POU3F2 protein (amino acids 220-421) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu POU3F2

Target: POU3F2 (POU Class 3 Homeobox 2 (POU3F2))

Andere Bezeichnung: POU3F2 (POU3F2 Produkte)

Synonyme: BRN2 antikoerper, N-Oct3 antikoerper, OCT7 antikoerper, OTF-7 antikoerper, OTF7 antikoerper, POUF3 antikoerper, brn-2 antikoerper, oct-7 antikoerper, XlPOU3 antikoerper, pou3f2 antikoerper, pou3f2-A antikoerper, pou3f4 antikoerper, 9430075J19Rik antikoerper, A230098E07Rik antikoerper, Brn-2 antikoerper, Brn2 antikoerper, Otf7 antikoerper, XLPOU3b antikoerper, pou47 antikoerper, zp47 antikoerper, zp47pou antikoerper, brn-1.2 antikoerper, brn1.2 antikoerper, id:ibd5088 antikoerper, POU class 3 homeobox 2 antikoerper, POU class 3 homeobox 2 L homeolog antikoerper, POU domain, class 3, transcription factor 2 antikoerper, POU class 3 homeobox 2 S homeolog antikoerper, POU class 3 homeobox 2b antikoerper, POU class 3 homeobox 2a antikoerper, POU3F2 antikoerper, pou3f2.L antikoerper, Pou3f2 antikoerper, pou3f2.S antikoerper, pou3f2b antikoerper, pou3f2a antikoerper

Hintergrund: POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter. POU3F2 is expressed exclusively in the central nervous system, more specifically in postmitotic neurons and glia.

Molekulargewicht: 27 kDa

Gen-ID: 5454

UniProt: P20265