POU3F2 Antikörper (AA 220-421)
Kurzübersicht für POU3F2 Antikörper (AA 220-421) (ABIN5027442)
Target
Alle POU3F2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 220-421
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Aufreinigung
- Protein A Chromatography
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Immunogen
- A partial length recombinant POU3F2 protein (amino acids 220-421) was used as the immunogen for this antibody.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1-2 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- POU3F2 (POU Class 3 Homeobox 2 (POU3F2))
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Andere Bezeichnung
- POU3F2
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Hintergrund
- POU3F2 is a developmental neural cell-specific POU domain transcription factor and is crucial for cell lineage determination. In melanoma lesions, cells expressing high levels of POU3F2 show enhanced invasive and metastatic capacity that can in part be explained by repression of MITF (Micropthalmia-associated Transcription Factor) expression via POU3F2 binding to its promoter. POU3F2 is expressed exclusively in the central nervous system, more specifically in postmitotic neurons and glia.
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Molekulargewicht
- 27 kDa
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Gen-ID
- 5454
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UniProt
- P20265
Target
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