PACS1 Antikörper (AA 150-400)

Produktnummer ABIN5027422

Der Kaninchen Polyklonal anti-PACS1 Antikörper wird verwendet zum Nachweis von PACS1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für PACS1 Antikörper (AA 150-400) (ABIN5027422)

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PACS1 Antikörper

Bindungsspezifität: AA 150-400

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant PACS-1 protein (amino acids 150-400) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-3 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu PACS1

Target: PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))

Andere Bezeichnung: PACS-1

Hintergrund: PACS1 or phosphofurin acidic cluster sorting protein 1 belongs to the PACS familyof proteins and is involved in protein trafficking. PACS1 contains an acidic cluster sorting motifs and plays an important role in the localization of trans-Golgi network (TGN) membrane proteins. It has also been implicated in secretory granule biogenesis. In order to enable HIV-1 to escape immune surveillance, PACS-1 is also reported to be involved in HIV-1 Nef-mediated removal of MHC-I from the cell surface to the trans-golgi network. Diseases caused by mutation in this gene include mental retardation (MRD17) and AIDS. PACS1 has expression in adipose tissue, liver, spleen, bone, blood, brain. It has 2 isoforms produced by alternative splicing.

Molekulargewicht: 106 kDa

Gen-ID: 55690

UniProt: Q6VY07