MUL1 Antikörper (AA 146-352)
Kurzübersicht für MUL1 Antikörper (AA 146-352) (ABIN5027374)
Target
Alle MUL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 146-352
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Aufreinigung
- Protein G Chromatography
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Immunogen
- A partial length recombinant MUL1 protein (amino acids 146-352) was used as the immunogen for this antibody.
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Isotyp
- IgG1
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anti-Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) (AA 45-95) antibody
MUL1 Reaktivität: Human, Maus, Ratte WB, IF (p), FACS, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) (Middle Region) antibodyMUL1 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) (AA 176-210) antibodyMUL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB49942 unconjugated
anti-Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) (AA 1-352) antibodyMUL1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) (AA 272-301), (C-Term) antibodyMUL1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB32336 unconjugated
anti-Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) (AA 216-265) antibodyMUL1 Reaktivität: Human, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Affe, Fledermaus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1) (AA 143-192) antibodyMUL1 Reaktivität: Human, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Affe WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 4-8 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
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Andere Bezeichnung
- MUL1
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Hintergrund
- MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.
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Molekulargewicht
- 40 kDa
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Gen-ID
- 79594
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UniProt
- Q969V5
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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