MEIS1 Antikörper (AA 163-352)

Produktnummer ABIN5027352

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MEIS1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MEIS1 Antikörper (AA 163-352) (ABIN5027352)

Target: MEIS1 (Meis Homeobox 1 (MEIS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEIS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MEIS1 Antikörper

Bindungsspezifität: AA 163-352

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant MEIS1 protein (amino acids 163-352) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu MEIS1

Target: MEIS1 (Meis Homeobox 1 (MEIS1))

Andere Bezeichnung: MEIS1

Hintergrund: Myeloid ecotropoic viral insertion site 1 (MEIS1) is a transcription factor belonging to TALE (three amino acids loop extension) family. The gene for MEIS1 is mapped to human chromosome 2p15. The amino terminus contains binding domains for its interaction partners, the transcription factors HOXA9 and PBX1, followed by a homeobox DNA binding domain and carboxy-terminal transcriptional activation domains. It is expressed in hematopoietic stem and progenitor cells and increases during human megakaryocytic differentiation. MEIS1 plays a role in the normal development of the hematopoietic lineage and is over expressed in a subset of acute myeloid leukemias. Increased MEIS1 expression has also been observed in neuroblastomas and the expression level of the MEIS1 transcript is a prognostic indicator in breast cancer.

Molekulargewicht: 43 kDa

Gen-ID: 4211

UniProt: O00470

Pathways: Chromatin Binding