MBD3 Antikörper (AA 1-290)
-
- Target Alle MBD3 Antikörper anzeigen
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
-
Bindungsspezifität
- AA 1-290
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser MBD3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Aufreinigung
- Protein G Chromatography
- Immunogen
- A partial length recombinant MBD3 protein (amino acids 1-290) was used as the immunogen for this antibody.
- Klon
- ABM14A8
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product MBD3 Primärantikörper
-
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 79-209) antibody
MBD3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (Glu279) antibodyMBD3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) antibodyMBD3 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 264-291), (C-Term) antibodyMBD3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB02375 unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 70-179) antibodyMBD3 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 1-291) antibodyMBD3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 1-255) antibodyMBD3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- WB: 2-4 μg/mL, IHC: 5 μg/mL, FACS: 0.5 μg/10^6 cells
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
- Target
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- Andere Bezeichnung
- MBD2/MBD3 (MBD3 Produkte)
- Synonyme
- xmbd3 antikoerper, MGC69548 antikoerper, MBD3 antikoerper, DKFZp459N1635 antikoerper, AI181826 antikoerper, AU019209 antikoerper, methyl-CpG binding domain protein 3 S homeolog antikoerper, methyl-CpG binding domain protein 3 antikoerper, mbd3.S antikoerper, mbd3 antikoerper, MBD3 antikoerper, Mbd3 antikoerper
- Hintergrund
- MBD2 is a subunit of the NuRD complex that is postulated to mediate gene repression via recruitment of the complex to methylated DNA. This protein binds around 1 kb downstream of the transcription start site of a subset of 400 CpG island promoters that are characterized by the presence of active histone marks, RNA polymerase II (Pol2) and low to medium gene expression levels and H3K36me3 deposition. Methylated MBD2 is involved in silencing methylated tumor suppressor genes as well as activation of pro-metastatic genes. MBD2 also plays a key role in regulating expression of a range of genes that are associated with optimal DC (Dendritic cells) activation and function.
- Molekulargewicht
- 32. 44 kDa
- Gen-ID
- 53615
- UniProt
- O95983
- Pathways
- Chromatin Binding
-
