KLF10/TIEG1 Antikörper (AA 11-221)

Produktnummer ABIN5027328

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KLF10/TIEG1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KLF10/TIEG1 Antikörper (AA 11-221) (ABIN5027328)

Target: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF10/TIEG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLF10/TIEG1 Antikörper

Bindungsspezifität: AA 11-221

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant KLF10 protein (amino acids 11-221) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu KLF10/TIEG1

Target: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Andere Bezeichnung: KLF10

Hintergrund: Kruppel-like factor 10 (KLF10 ) is a member of the Kruppel-like family of transcription factors, which are known to be involved in anti-proliferative and apoptotic inducing functions following TGF-beta induction. KLF10 plays an important role in the repression of proliferative and hypertrophic pathways, possibly through the actions of PTTG1 (pituitary tumor-transforming gene 1). KLF10 is found to be predominantly expressed in various tissues and its expression is regulated by cytokines and growth factors. Over-expression of KLF10 has been found to induce apoptosis in pancreatic cancer cells. In addition, KLF10 induces apoptosis via a mechanism which involves the formation of reactive oxygen species.

Molekulargewicht: 46 kDa

Gen-ID: 7071

UniProt: Q13118

Pathways: Stem Cell Maintenance