JMJD5 Antikörper (AA 20-220)
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- Target Alle JMJD5 Antikörper anzeigen
- JMJD5 (Jumonji Domain Containing 5 (JMJD5))
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Bindungsspezifität
- AA 20-220
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser JMJD5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Protein A Chromatography
- Immunogen
- A partial length recombinant JMJD5 protein (amino acids 20-220) was used as the immunogen for this antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product JMJD5 Primärantikörper
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- Applikationshinweise
- WB: 2-4 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Target
- JMJD5 (Jumonji Domain Containing 5 (JMJD5))
- Andere Bezeichnung
- JMJD5 (JMJD5 Produkte)
- Synonyme
- jmjd5 antikoerper, JMJD5 antikoerper, 3110005O21Rik antikoerper, Jmjd5 antikoerper, zgc:173863 antikoerper, zgc:91962 antikoerper, RGD1304823 antikoerper, lysine demethylase 8 antikoerper, jumonji domain containing 5 antikoerper, hypothetical protein antikoerper, lysine (K)-specific demethylase 8 antikoerper, KDM8 antikoerper, PTRG_02386 antikoerper, MCYG_00400 antikoerper, CC1G_13927 antikoerper, PGTG_16928 antikoerper, kdm8 antikoerper, Kdm8 antikoerper
- Hintergrund
- JMJD5 (Jumonji domain-containing protein 5) or commonly called as Lysine-specific demethylase 8 is a histone lysine demethylase that specifically demethylates dimethylated Lys 36 of histone H3 (H3K36me2) thereby activating the target gene. JMJD5 is important for G2/M phase cell cycle progression. JMJD5 is also a potential tumor suppression protein. JMJD5 helps in regulation of cancer proliferation by regulating cyclin-A1. JMJD5 has three isoforms (47, 24, 50 kDa), all localized in nucleus. JMJD5 is weakly expressed in most normal cells but highly expressed in breast cancer cells.
- Molekulargewicht
- 47 kDa
- Gen-ID
- 79831
- UniProt
- Q8N371
- Pathways
- Chromatin Binding
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