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JMJD5 Antikörper (AA 20-220)

JMJD5 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5027324
  • Target Alle JMJD5 Antikörper anzeigen
    JMJD5 (Jumonji Domain Containing 5 (JMJD5))
    Bindungsspezifität
    • 15
    • 10
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-220
    Reaktivität
    • 38
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    • 3
    Kaninchen
    Klonalität
    • 36
    • 2
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser JMJD5 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 20
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Protein A Chromatography
    Immunogen
    A partial length recombinant JMJD5 protein (amino acids 20-220) was used as the immunogen for this antibody.
    Isotyp
    IgG
    Top Product
    Discover our top product JMJD5 Primärantikörper
  • Applikationshinweise
    WB: 2-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    JMJD5 (Jumonji Domain Containing 5 (JMJD5))
    Andere Bezeichnung
    JMJD5 (JMJD5 Produkte)
    Synonyme
    jmjd5 antikoerper, JMJD5 antikoerper, 3110005O21Rik antikoerper, Jmjd5 antikoerper, zgc:173863 antikoerper, zgc:91962 antikoerper, RGD1304823 antikoerper, lysine demethylase 8 antikoerper, jumonji domain containing 5 antikoerper, hypothetical protein antikoerper, lysine (K)-specific demethylase 8 antikoerper, KDM8 antikoerper, PTRG_02386 antikoerper, MCYG_00400 antikoerper, CC1G_13927 antikoerper, PGTG_16928 antikoerper, kdm8 antikoerper, Kdm8 antikoerper
    Hintergrund
    JMJD5 (Jumonji domain-containing protein 5) or commonly called as Lysine-specific demethylase 8 is a histone lysine demethylase that specifically demethylates dimethylated Lys 36 of histone H3 (H3K36me2) thereby activating the target gene. JMJD5 is important for G2/M phase cell cycle progression. JMJD5 is also a potential tumor suppression protein. JMJD5 helps in regulation of cancer proliferation by regulating cyclin-A1. JMJD5 has three isoforms (47, 24, 50 kDa), all localized in nucleus. JMJD5 is weakly expressed in most normal cells but highly expressed in breast cancer cells.
    Molekulargewicht
    47 kDa
    Gen-ID
    79831
    UniProt
    Q8N371
    Pathways
    Chromatin Binding
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