JMJD5 Antikörper (AA 20-220)
Kurzübersicht für JMJD5 Antikörper (AA 20-220) (ABIN5027324)
Target
Alle JMJD5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 20-220
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Aufreinigung
- Protein A Chromatography
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Immunogen
- A partial length recombinant JMJD5 protein (amino acids 20-220) was used as the immunogen for this antibody.
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Isotyp
- IgG
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Applikationshinweise
- WB: 2-4 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- JMJD5 (Jumonji Domain Containing 5 (JMJD5))
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Andere Bezeichnung
- JMJD5
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Hintergrund
- JMJD5 (Jumonji domain-containing protein 5) or commonly called as Lysine-specific demethylase 8 is a histone lysine demethylase that specifically demethylates dimethylated Lys 36 of histone H3 (H3K36me2) thereby activating the target gene. JMJD5 is important for G2/M phase cell cycle progression. JMJD5 is also a potential tumor suppression protein. JMJD5 helps in regulation of cancer proliferation by regulating cyclin-A1. JMJD5 has three isoforms (47, 24, 50 kDa), all localized in nucleus. JMJD5 is weakly expressed in most normal cells but highly expressed in breast cancer cells.
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Molekulargewicht
- 47 kDa
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Gen-ID
- 79831
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UniProt
- Q8N371
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Pathways
- Chromatin Binding
Target
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