IPO9
Reaktivität: Human
WB, ELISA, ICC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 0.25-1.0 μg/mL, IHC: 5 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target
Importin 9 (IPO9)
Andere Bezeichnung
Importin-9 (Ran-binding protein 9)
Hintergrund
Importin-9 (IPO9) is a molecular transporter and chaperone that belongs to the super-family of karyopherins. It binds primarily to stem-loop structure 1 in IFN-epsilon5'UTR, and negatively impacts mRNA expression. Importins, including Importin-9, are known for their ability to mediate active transport through nuclear pore complexes and effectively suppress the aggregation of their basic import cargoes in polyanionic environments. Importins exert their functions through protein-protein interactions, they recognize nuclear localization signals and prevent protein aggregation by shielding basic patches such as those found in a variety of ribosomal proteins.