IPO7 Antikörper (AA 1-322)

Produktnummer ABIN5027310

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IPO7 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IPO7 Antikörper (AA 1-322) (ABIN5027310)

Target: IPO7 (Importin 7 (IPO7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IPO7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IPO7 Antikörper

Bindungsspezifität: AA 1-322

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant Importin 7 protein (amino acids 1-322) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu IPO7

Target: IPO7 (Importin 7 (IPO7))

Andere Bezeichnung: Importin 7

Hintergrund: Importin 7 (IPO7) is a soluble nuclear transport factor that is required for efficient import. It mediates transport of hTERT into the nucleus. Efficient transport also requires the cytoplasmic nucleoporin Nup358, which was previously implicated in nuclear import of a subset of proteins. Importin 7 plays an important role in nuclear protein import either by acting as autonomous nuclear transport receptor, or as an adapter like protein in association with the importin-beta subunit KPNB1. It serves itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism.

Molekulargewicht: 115 kDa

Gen-ID: 10527

UniProt: O95373

Pathways: Protein targeting to Nucleus