HOXA9 Antikörper (AA 63-272)

Produktnummer ABIN5027256

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HOXA9 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HOXA9 Antikörper (AA 63-272) (ABIN5027256)

Target: HOXA9 (Homeobox A9 (HOXA9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HOXA9 Antikörper

Bindungsspezifität: AA 63-272

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant HOXA9 protein (amino acids 63-272) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu HOXA9

Target: HOXA9 (Homeobox A9 (HOXA9))

Andere Bezeichnung: HOXA9

Hintergrund: HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide) . In humans,HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients.

Molekulargewicht: 30 kDa

Gen-ID: 3205

UniProt: P31269