guanylate binding protein 1 antikoerper, guanylate binding protein 1, interferon-inducible antikoerper, guanylate binding protein 1, interferon-inducible, 67kD antikoerper, GBP1 antikoerper, Gbp1 antikoerper, gbp1 antikoerper
Hintergrund
Interferon-induced guanylate-binding protein 1 in humans is encoded by the GBP1 gene belongs to the dynamin superfamily of large GTPases and induced by interferons. GBP1 hydrolyzes GTP to GMP in two consecutive cleavage reactions and also exhibits antiviral activity against influenza virus. Diseases associated with GBP1 include pseudo pseudo hypoparathyroidism and aneurysmal bone cysts. It is widely expressed on central nervous system, mammary gland, skeletal muscle, skin, small intestine, stomach, etc.