DMAP1
Reaktivität: Human
WB
Wirt: Kaninchen
Monoclonal
unconjugated
Applikationshinweise
WB: 2-4 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target
DMAP1
(DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
Andere Bezeichnung
DMAP1
Hintergrund
DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene and consisting of 433 aminoacids. It is involved in transcription repression and activation. DMAP1 interacts with HDAC2 which provides a mechanism for histone deacetylation in heterochromatin following replication of DNA at late dismissal origins. DMAP1 can also repress transcription independently of histone deacetylase activity. It participates in the nuclear localization of URI1 and increases its transcriptional co-repressor activity. It is expressed in adipose tissue, adrenal gland, amniotic fluid, cerebellar cortex, hippocampus, liver, etc.