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Desmoglein 3 Antikörper (AA 328-526)

DSG3 Reaktivität: Human IHC Wirt: Maus Monoclonal ABM4A31 unconjugated
Produktnummer ABIN5027152
  • Target Alle Desmoglein 3 (DSG3) Antikörper anzeigen
    Desmoglein 3 (DSG3)
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 328-526
    Reaktivität
    • 65
    • 21
    • 16
    Human
    Wirt
    • 61
    • 24
    Maus
    Klonalität
    • 60
    • 25
    Monoklonal
    Konjugat
    • 34
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Desmoglein 3 Antikörper ist unkonjugiert
    Applikation
    • 63
    • 35
    • 19
    • 17
    • 15
    • 13
    • 13
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Aufreinigung
    Protein G Chromatography
    Immunogen
    A partial length recombinant Desmoglein 3 protein (amino acids 328-526) was used as the immunogen for this antibody.
    Klon
    ABM4A31
    Isotyp
    IgG2b kappa
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  • Applikationshinweise
    IHC: 1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    Desmoglein 3 (DSG3)
    Andere Bezeichnung
    Desmoglein 3 (DSG3 Produkte)
    Synonyme
    DSG3 antikoerper, CDHF6 antikoerper, PVA antikoerper, bal antikoerper, balding antikoerper, desmoglein 3 antikoerper, DSG3 antikoerper, Dsg3 antikoerper
    Hintergrund
    DSG3 (Desmoglein 3) is a calcium-binding transmembrane glycoprotein component of desmosomes, conferring strong cell-cell adhesion. Desmosomes are button-like points of intercellular contact that allow the attachment of cytoskeletal elements to the plasma membrane at sites of cell-cell adhesion. DSG3 is expressed in basal and immediate suprabasal layers of skin. To maintain cell-cell adhesion DSG3 interacts with other desmosomal proteins, such as plakoglobin. Plakoglobin is closely related to Beta-catenin, which is a well-known downstream effector molecule in the canonical Wnt signaling pathway.DSG3 also promotes cancer cell growth and invasion through a plakoglobin-mediated signaling pathway.
    Gen-ID
    1830
    UniProt
    P32926
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