Desmoglein 3 Antikörper (AA 328-526)
Kurzübersicht für Desmoglein 3 Antikörper (AA 328-526) (ABIN5027152)
Target
Alle Desmoglein 3 (DSG3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 328-526
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Aufreinigung
- Protein G Chromatography
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Immunogen
- A partial length recombinant Desmoglein 3 protein (amino acids 328-526) was used as the immunogen for this antibody.
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Isotyp
- IgG2b kappa
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anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human IHC Wirt: Maus Monoclonal DSG3-2840 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human IHC Wirt: Maus Monoclonal 543M unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reaktivität: Human WB, IHC, IF, FACS Wirt: Maus Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal DSG3-2796 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reaktivität: Human IHC, ICC Wirt: Maus Monoclonal BC11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated
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Applikationshinweise
- IHC: 1 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Desmoglein 3 (DSG3)
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Andere Bezeichnung
- Desmoglein 3
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Hintergrund
- DSG3 (Desmoglein 3) is a calcium-binding transmembrane glycoprotein component of desmosomes, conferring strong cell-cell adhesion. Desmosomes are button-like points of intercellular contact that allow the attachment of cytoskeletal elements to the plasma membrane at sites of cell-cell adhesion. DSG3 is expressed in basal and immediate suprabasal layers of skin. To maintain cell-cell adhesion DSG3 interacts with other desmosomal proteins, such as plakoglobin. Plakoglobin is closely related to Beta-catenin, which is a well-known downstream effector molecule in the canonical Wnt signaling pathway.DSG3 also promotes cancer cell growth and invasion through a plakoglobin-mediated signaling pathway.
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Gen-ID
- 1830
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UniProt
- P32926
Target
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