DLL3 Antikörper (AA 62-286)

Produktnummer ABIN5027148

Produktdetails anti-DLL3 Antikörper

Target: DLL3 (delta Like Protein 3 (DLL3))

Bindungsspezifität: AA 62-286

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant Delta like 3 protein (amino acids 62-286) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu DLL3

Target: DLL3 (delta Like Protein 3 (DLL3))

Andere Bezeichnung: Delta like 3 (DLL3 Produkte)

Synonyme: SCDO1 antikoerper, pu antikoerper, pudgy antikoerper, delta like canonical Notch ligand 3 antikoerper, delta-like 3 (Drosophila) antikoerper, DLL3 antikoerper, Dll3 antikoerper

Hintergrund: Delta like 3 (DLL3) is a member of Delta/Serrate/Lag2 (DSL) ligands for Notch receptors and plays a role in Notch signaling. Out of Five DSL ligands, DLL3 is the most structurally divergent DSL ligand. DLL3 is expressed throughout the presomitic mesoderm and is localized to the rostral somatic compartments. Homozygous disruptions of Notch1 and DLL3 result in severe abnormalities in somitogenesis. Mutations in the human DLL3 homolog cause recessive skeletal abnormalities in spondylocostal dysostosis with a consistent pattern of abnormal segmentation.

Molekulargewicht: 65 kDa

Gen-ID: 10683

UniProt: Q9NYJ7

Pathways: Notch Signalweg