CUEDC2 Antikörper (AA 100-280)

Produktnummer ABIN5027122

Der Kaninchen Polyklonal anti-CUEDC2 Antikörper wird verwendet zum Nachweis von CUEDC2 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CUEDC2 Antikörper (AA 100-280) (ABIN5027122)

Target: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CUEDC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CUEDC2 Antikörper

Bindungsspezifität: AA 100-280

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant CUEDC2 protein (amino acids 100-280) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu CUEDC2

Target: CUEDC2 (CUE Domain Containing 2 (CUEDC2))

Andere Bezeichnung: CUEDC2

Hintergrund: CUE domain-containing protein 2 commonly known as CUEDC2 is a 32 kDa protein having CUE Domain. It is involved in ubiquitin and proteasome-mediated degradation of progesterone receptor and estrogen receptor. It interacts with PRB isoform of progesterone receptor (PR) and modulates estrogen receptor (ER)-alpha protein stability through the ubiquitin-proteasome pathway. High level expression of CUEDC2 found in breast cancer tissue compared to normal adjacent tissue. It is found that CUEDC2 has some role in regulating IKK dephosphorylation by recruiting PP1.

Molekulargewicht: 30 kDa

Gen-ID: 79004

UniProt: Q9H467