Calretinin Antikörper (AA 4-238)

Produktnummer ABIN5027071

Der Kaninchen Polyklonal Anti-Calretinin-Antikörper wurde für WB validiert. Er ist geeignet, Calretinin in Proben von Human zu detektieren.

Kurzübersicht für Calretinin Antikörper (AA 4-238) (ABIN5027071)

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calretinin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Calretinin Antikörper

Bindungsspezifität: AA 4-238

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant Calretinin protein (amino acids 4-238) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Andere Bezeichnung: Calretinin

Hintergrund: Calretinin is a 29-kD intracellular, vitamin D-dependent calcium binding protein that likely has multiple functional roles including intracellular calcium buffering and message targeting. This protein is a member of the EF-hand family of calcium-binding proteins and first identified in the central nervous system. It has also been identified in a wide variety of non-neural cells, both neoplastic and non-neoplastic. In the oncologic arena calretinin is most commonly used as part of a panel in the separation of pleural mesothelioma from poorly differentiated pulmonary adenocarcinomas. While in most cases highly sensitive and specific for mesothelial origin, calretinin positivity has been reported in carcinomas arising in a myriad of other tissues including ovary, testis, adrenal cortex, colon, breast, sinonasal tract, thymus, skin and even soft tissue.

Molekulargewicht: 31 kDa

Gen-ID: 794

UniProt: P22676