T-Box 1 Antikörper (AA 200-410)

Produktnummer ABIN5027059

Der Kaninchen Polyklonal Anti-T-Box 1-Antikörper wurde für WB validiert. Er ist geeignet, T-Box 1 in Proben von Human zu detektieren.

Kurzübersicht für T-Box 1 Antikörper (AA 200-410) (ABIN5027059)

Target: T-Box 1 (TBX1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser T-Box 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-T-Box 1 Antikörper

Bindungsspezifität: AA 200-410

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant Brachyury protein (amino acids 200-410) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu T-Box 1

Target: T-Box 1 (TBX1)

Andere Bezeichnung: Brachyury

Hintergrund: Brachyury is a transcription factor encoded by T, a member of the T-box gene family, and required for posterior mesoderm formation and differentiation as well as for notochord development. It is expressed in all nascent mesoderm, in the embryo. Along with embryonic differentiation, it is downregulated, restricted into the notochord and the tail bud, and then lost, when notochordal cells are replaced by bone in the vertebral bodies and by the nucleus pulposus in the intervertebral discs. In the adult, brachyury expression has been found in chordoma, a malignant tumor which recapitulates notochord and derives from small collections of notochordal cells which may persist into the adult life.

Molekulargewicht: 55 kDa

Gen-ID: 6862

UniProt: O15178

Pathways: Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation