Elastase Antikörper

Produktnummer ABIN5026899

Der Huhn Polyklonal Anti-Elastase-Antikörper wurde für ELISA, WB, IHC und AGG validiert. Er ist geeignet, Elastase in Proben von Säugetier zu detektieren.

Kurzübersicht für Elastase Antikörper (ABIN5026899)

Target: Elastase

Reaktivität: Säugetier

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser Elastase Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Agglutination (AGG)

Produktdetails anti-Elastase Antikörper

Produktmerkmale: IgY-antibody

Aufreinigung: Precipitation with ammoniumsulfate , dialyse and fitration

Immunogen: raw, native protein

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: Perform a chessboard titation before the first application

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, 0.1 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Details zu Elastase

Target: Elastase

Hintergrund: Secreted by neutrophils and macrophages during inflammation, elastase is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity, destroys bacteria and host tissue. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. It is also an important protease enzyme that when expressed aberrantly can cause emphysema or emphysematous changes. This involves breakdown of the lung structure and increased airspaces.