MLXIPL Antikörper (AA 81-180) (AbBy Fluor® 750)

Produktnummer ABIN5012474

Dieses Anti-MLXIPL-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MLXIPL in IF (cc) und IF (p). Geeignet für Ratte.

Kurzübersicht für MLXIPL Antikörper (AA 81-180) (AbBy Fluor® 750) (ABIN5012474)

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLXIPL Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MLXIPL Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 81-180

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WBSCR14/ChREBP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MLXIPL

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Andere Bezeichnung: WBSCR14

Hintergrund:

Synonyms: ChREBP, bHLHd14, Carbohydrate responsive element binding protein, MIO, MLX interacting protein like, Mlx interactor, MLXIPL, MONDOB, WBSCR 14, WBSCR14, Williams Beuren syndrome chromosome region 14, Williams Beuren syndrome chromosome region 14 protein, WS basic helix loop helix leucine zipper protein, WS bHLH, MLXPL_HUMAN.

Background: ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain.ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of serine 196.

Gen-ID: 51085

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process