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MLXIPL Antikörper (AA 81-180) (AbBy Fluor® 750)

Dieses Anti-MLXIPL-Antikörper ist ein Rabbit Polyclonal-Antikörper zur Detektion von MLXIPL in IF (cc), IF (p). Geeignet für Rat.
Produktnummer ABIN5012474

Kurzübersicht für MLXIPL Antikörper (AA 81-180) (AbBy Fluor® 750) (ABIN5012474)

Target

Alle MLXIPL Antikörper anzeigen
MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Reaktivität

  • 38
  • 24
  • 13
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Ratte

Wirt

  • 49
  • 3
Kaninchen

Klonalität

  • 49
  • 3
Polyklonal

Konjugat

  • 25
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MLXIPL Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation

  • 27
  • 15
  • 14
  • 12
  • 12
  • 10
  • 9
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 81-180

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Cow,Pig,Horse,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human WBSCR14/ChREBP

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    MLXIPL (MLX Interacting Protein-Like (MLXIPL))

    Andere Bezeichnung

    WBSCR14

    Hintergrund

    Synonyms: ChREBP, bHLHd14, Carbohydrate responsive element binding protein, MIO, MLX interacting protein like, Mlx interactor, MLXIPL, MONDOB, WBSCR 14, WBSCR14, Williams Beuren syndrome chromosome region 14, Williams Beuren syndrome chromosome region 14 protein, WS basic helix loop helix leucine zipper protein, WS bHLH, MLXPL_HUMAN.

    Background: ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain.ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of serine 196.

    Gen-ID

    51085

    Pathways

    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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