UGDH Antikörper (AA 421-494) (AbBy Fluor® 750)
Kurzübersicht für UGDH Antikörper (AA 421-494) (AbBy Fluor® 750) (ABIN5012226)
Target
Alle UGDH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 421-494
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Dog,Cow,Sheep,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human UGDH/UDPGDH
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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Andere Bezeichnung
- UGDH
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Hintergrund
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Synonyms: UDP glucose dehydrogenase, GDH, UDP Glc dehydrogenasev UDP GlcDH, UDP glucose 6 dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH, UGD, Ugdh, UGDH_HUMAN, Uridine diphospho glucose dehydrogenase.
Background: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
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Gen-ID
- 7358
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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