TRIM25 Antikörper (pSer100) (AbBy Fluor® 680)

Produktnummer ABIN5011931

Dieses Anti-TRIM25-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRIM25 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für TRIM25 Antikörper (pSer100) (AbBy Fluor® 680) (ABIN5011931)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TRIM25 Antikörper (AbBy Fluor® 680)

Bindungsspezifität: pSer100

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human TRIM25 around the phosphorylation site of Ser100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25

Hintergrund:

Synonyms: TRIM25phospho S100_EFP, Estrogen responsive finger protein, RNF 147, RNF147, TRI25, TRIM 25, Tripartite mot containing 25, Tripartite mot containing protein 25, Z147, Zinc finger protein 147, Zinc finger protein 147 estrogen responsive finger protein, ZNF 147, ZNF147.

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein localizes to the cytoplasm. The presence of potential DNA binding and dimerization transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Gen-ID: 7706