ZSCAN4 Antikörper (C-Term)

Produktnummer ABIN501165

Der Kaninchen Polyklonal anti-ZSCAN4 Antikörper (ABIN501165) detektiert spezifisch ZSCAN4 in WB, IHC (p) und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ZSCAN4 Antikörper (C-Term) (ABIN501165)

Target: ZSCAN4 (Zinc Finger and SCAN Domain Containing 4 (ZSCAN4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZSCAN4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-ZSCAN4 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography

Immunogen: 18 amino acid peptide near the carboxy terminus of human ZSCAN4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Immunohistochemistry on paraffin sections. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu ZSCAN4

Target: ZSCAN4 (Zinc Finger and SCAN Domain Containing 4 (ZSCAN4))

Andere Bezeichnung: ZSCAN4

Hintergrund: Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintenance and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.Synonyms: ZNF494, Zinc finger and SCAN domain-containing protein 4, Zinc finger protein 494

Gen-ID: 201516

NCBI Accession: NP_689890