Syntaxin 6 Antikörper (AA 161-255) (AbBy Fluor® 750)

Produktnummer ABIN5011271

Dieses Anti-Syntaxin 6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Syntaxin 6 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für Syntaxin 6 Antikörper (AA 161-255) (AbBy Fluor® 750) (ABIN5011271)

Target: Syntaxin 6 (STX6)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Syntaxin 6 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Syntaxin 6 Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 161-255

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Syntaxin 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Syntaxin 6

Target: Syntaxin 6 (STX6)

Andere Bezeichnung: Syntaxin 6

Hintergrund:

Synonyms: STX 6, STX6, STX-6, STX6_HUMAN, Syntaxin-6, Syntaxin6.

Background: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain carboxy-terminal hydrophobic domains that direct themselves to their respective intracellular compartments. Synaptin 6 is a 255 amino acid protein that is widely expressed, with higher expression levels in brain, lung and kidney. This synaptin co-localizes with vesicle associated membrane protein (VAMP) 4 to tubular and vesicular membranes of the Golgi apparatus. The cytosolic domain of Syntaxin 6 reduces the rate on Glut4 reinternalization upon insulin withdrawl and is involved in a memrane-trafficking process that removes Glut4 from traffic directed to the plasma membrane. Syntaxin 6 is upregulated in activated macrophages in conjunction with an increase in the secretion of cytokines. The delivery of microdomain-associated lipids and proteins to the cell surface is regulated by Syntaxin 6.

Pathways: Synaptic Vesicle Exocytosis