Midline 2 Antikörper (AA 251-350) (AbBy Fluor® 680)

Produktnummer ABIN5009985

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Midline 2 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Midline 2 Antikörper (AA 251-350) (AbBy Fluor® 680) (ABIN5009985)

Target: Midline 2 (MID2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Midline 2 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Midline 2 Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 251-350

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RNF60/Midline-2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Midline 2

Target: Midline 2 (MID2)

Andere Bezeichnung: RNF60/Midline-2

Hintergrund:

Synonyms: FXY2, MID2, Midin-2, Midline 2, Midline defect 2, Midline-2, Probable E3 ubiquitin-protein ligase MID2, RING finger protein 60, Ring finger protein protein 60, RNF60, TRIM1, TRIM1_HUMAN, Tripartite mot protein 1, Tripartite mot-containing protein 1, Tripartite mot-containing protein 1, Midline defect 2, FLJ37715, FLJ41813.

Background: Midline-2 is a 715 amino acid protein encoded by the human gene MID2. Midline-2 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-2 is a cytoplasmic protein found as a homodimer or heterodimer with Midline-1. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Dimerization is mediated by the tripartite motif (RBCC, RING- and B box-type zinc fingers and coiled coil domains) and microtubule association is dependent on the C-terminal B30.2 domain. Midline-2 is expressed at low levels in fetal kidney and lung, and in adult prostate, ovary and small intestine.

Gen-ID: 26040