Transmembrane Protein 70 (TMM70) (Center) Antikörper

Produktnummer ABIN500988

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Transmembrane Protein 70 (TMM70) (Center) Antikörper (ABIN500988)

Target: Transmembrane Protein 70 (TMM70)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails

Bindungsspezifität: Center

Spezifität: This antibody detects TMEM70.

Aufreinigung: Peptide affinity chromatography

Immunogen: TMEM70 antibody was raised against a 14 amino acid peptide near the center of human TMEM70.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Antigendetails

Target: Transmembrane Protein 70 (TMM70)

Andere Bezeichnung: TMEM70

Hintergrund: TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.Synonyms: Transmembrane protein 70, mitochondrial

Gen-ID: 54968

NCBI Accession: NP_060336