PON3 Antikörper (AA 201-300) (AbBy Fluor® 750)

Produktnummer ABIN5009053

Der Kaninchen Polyklonal Anti-PON3-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, PON3 in Proben von Human zu detektieren.

Kurzübersicht für PON3 Antikörper (AA 201-300) (AbBy Fluor® 750) (ABIN5009053)

Target: PON3 (Paraoxonase 3 (PON3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PON3 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PON3 Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 201-300

Homologie: Human,Mouse,Rat,Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PON3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PON3

Target: PON3 (Paraoxonase 3 (PON3))

Andere Bezeichnung: PON3

Hintergrund:

Synonyms: paraoxonase 3, paraoxonase3, Pon3, PON3_HUMAN, Serum paraoxonase/lactonase 3, 2810004E20, AI786302, MGC95026.

Background: Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.

Pathways: Monocarboxylic Acid Catabolic Process