PDZK1 Antikörper (AbBy Fluor® 750)

Produktnummer ABIN5008638

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PDZK1 in WB und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PDZK1 Antikörper (AbBy Fluor® 750) (ABIN5008638)

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDZK1 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PDZK1 Antikörper (AbBy Fluor® 750)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDZK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PDZK1

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Andere Bezeichnung: PDZK1

Hintergrund:

Synonyms: CAP70, CFTR associated protein of 70 kDa, CFTR associated protein, 70-KD, CFTR-associated protein of 70 kDa, CLAMP, D3Ertd537e, Dietary Pi-regulated RNA-1, Diphor-1, mPDZK1, Na+/H+ exchange regulatory cofactor NHE-RF3, Na+/H+ exchanger regulatory factor 3, Na/Pi cotransporter C-terminal-associated protein 1, Na/Pi cotransporter C-terminal-associated protein, NaPi Cap1, NaPi-Cap1, NaPiCap1, NHERF 3, NHERF-3, NHERF3, NHRF3_HUMAN, OTTHUMP00000015572, PDZ domain containing 1, PDZ domain containing protein 1, PDZ domain-containing protein 1, PDZD1, PDZK1, Sodium hydrogen exchanger regulatory factor 3, Sodium-hydrogen exchanger regulatory factor 3, 1700023D20Rik, 2610507N21Rik, 4921513F16Rik, AI267131, AI314638, AL022680, C terminal linking and modulating protein.

Background: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

Gen-ID: 5174