Synaptogyrin 1 Antikörper (Center)

Produktnummer ABIN500843

Produktdetails anti-Synaptogyrin 1 Antikörper

Target: Synaptogyrin 1 (SYNGR1)

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Synaptogyrin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects Synaptogyrin-1 / SYNGR1.

Aufreinigung: Peptide affinity chromatography

Immunogen: SYNGR1 antibody was raised against a 16 amino acid peptide from near the center of human SYNGR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Synaptogyrin 1

Target: Synaptogyrin 1 (SYNGR1)

Andere Bezeichnung: Synaptogyrin-1 / SYNGR1 (SYNGR1 Produkte)

Hintergrund: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia, however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.

Gen-ID: 9145

Pathways: Regulation of long-term Neuronal Synaptic Plasticity